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| Nomenclature |
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Symbol:
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Rxrbtm1Pcn
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Name:
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retinoid X receptor beta;
targeted mutation 1, Pierre Chambon
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MGI ID: |
MGI:3611570 |
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Synonyms: |
RXRbetaL2 |
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Gene:
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Rxrb
Location:
Chr17:34031812-34038393 bp, + strand
Genetic Position: Chr17,
17.98 cM
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Rxratm4Ipc/Rxratm4Ipc Rxrbtm1Pcn/Rxrbtm1Pcn Tg(KRT14-cre/ERT2)1Ipc/0 mice develop a chronic skin inflammation
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:102470
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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LoxP sites flank exons 3 and 4, which encode the B and C regions and the Nt amino acids of region D. (J:102470, J:109510)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rxrb Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:102470
Li M et al.,
"Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin."
Proc Natl Acad Sci U S A 2005 Oct 11;102(41):14795-800
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All: |
6 reference(s)
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Analysis Tools
