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| Nomenclature |
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Symbol:
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Ptch1tm1Kmmt
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Name:
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patched homolog 1;
targeted mutation 1, Hiroyuki Kumamoto
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MGI ID: |
MGI:3609560 |
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Synonyms: |
ptc- |
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Gene:
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Ptch1
Location:
Chr13:63511533-63565520 bp, - strand
Genetic Position: Chr13,
32.8 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:102978
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 6 and 7 were replaced with an MC1-neomycin resistance gene via homologous recombination in ES cells. (J:102978)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ptch1 Mutation:
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22 strains or lines available |
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| References |
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Original: |
J:102978
Kimi K et al.,
"Immunohistochemical and genetic analysis of mandibular cysts in heterozygous ptc knockout mice."
J Oral Pathol Med 2003 Feb;32(2):108-13
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All: |
1 reference(s)
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Analysis Tools
