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| Nomenclature |
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Symbol:
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Tg(Tek-cre)1Rwng
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Name:
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transgene insertion 1, Rong Wang
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MGI ID: |
MGI:3608912 |
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Synonyms: |
Tg(Tek-cre)1Lfr, tie2-cre, Tie2Cre |
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Transgene:
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Tg(Tek-cre)1Rwng
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: The endothelial specific receptor tyrosine kinase promoter was used to drive expression of cre recombinase. Nine founder lines were produced and one of these was selected for use that efficiently mediated gene excision. Cre was active in the blood islands of extraembryonic mesoderm at E7.5 and in the dorsal aortae at E8.5. By E11.5 it was active in the endothelial cells of all blood vessels. (J:102190, J:104401)
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Recombinase activity
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Activity:
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 Tissue activity of this recombinase allele
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Driver:
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Tek
Summary of all recombinase alleles
driven by Tek.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:102190
Proctor JM et al.,
"Vascular development of the brain requires beta8 integrin expression in the neuroepithelium."
J Neurosci 2005 Oct 26;25(43):9940-8
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All: |
7 reference(s)
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Analysis Tools
