|
|
| Nomenclature |
|
Symbol:
|
Cx3cr1tm1Zm
|
|
Name:
|
chemokine (C-X3-C) receptor 1;
targeted mutation 1, Ziad Mallat
|
|
MGI ID: |
MGI:3608773 |
|
Synonyms: |
CX3CR1 KO |
|
Gene:
|
Cx3cr1
Location:
Chr9:120048693-120068282 bp, - strand
Genetic Position: Chr9,
71.37 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:103047
|
|
Parent Cell Line:
| Other (see notes) (ES Cell) |
|
Strain of Origin:
|
129
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A 600 bp fragment, including the start codon and 382 bp of coding region, was replaced with a neo cassette via homologous recombination. (J:103047)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Cx3cr1 Mutation:
|
28 strains or lines available |
|
|
Notes |
ES cell line = R1.211
|
| References |
|
Original: |
J:103047
Combadiere C et al.,
"Decreased atherosclerotic lesion formation in CX3CR1/apolipoprotein E double knockout mice."
Circulation 2003 Feb 25;107(7):1009-16
|
|
All: |
28 reference(s)
|
|
Analysis Tools
