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| Nomenclature |
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Symbol:
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Tg(KRT14-Kitl)1Takk
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Name:
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transgene insertion 1, Takahiro Kunisada
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MGI ID: |
MGI:3607790 |
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Synonyms: |
K14-Scf, Kitl-Tg, KRT14-Kitl, SCF-Tg, Tg(KRT14-itl)1Takk |
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Transgene:
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Tg(KRT14-Kitl)1Takk
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x SJL)F1
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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The human cytokeratin 14 upstream region was used to drive expression of kit ligand. (J:49253)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
(C57BL x SJL) F1 fertilized oocytes were microinjected with the vector.
Phenotypic Similarity to Human Syndrome: Cutaneous Malignant Melanoma in mice hemizygous for this transgene and homozygous for this allele Xpatm1Tnka
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| References |
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Original: |
J:49253
Kunisada T et al.,
"Transgene expression of steel factor in the basal layer of epidermis promotes survival, proliferation, differentiation and migration of melanocyte precursors."
Development 1998 Aug;125(15):2915-23
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All: |
13 reference(s)
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Analysis Tools
