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| Nomenclature |
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Symbol:
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Acadvltm1Vje
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Name:
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acyl-Coenzyme A dehydrogenase, very long chain;
targeted mutation 1, Vernat J Exil
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MGI ID: |
MGI:3606688 |
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Synonyms: |
VLCAD- |
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Gene:
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Acadvl
Location:
Chr11:70010183-70015411 bp, - strand
Genetic Position: Chr11,
42.96 cM, cytoband B2-B5
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:98627
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance gene in opposite orientation of endogenous transcription replaced exons 1 through 7. Northern blot of heart and muscle from mutants confirmed complete absence of mRNA. (J:98627)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Acadvl Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:98627
Exil VJ et al.,
"Very-long-chain acyl-coenzyme a dehydrogenase deficiency in mice."
Circ Res 2003 Sep 5;93(5):448-55
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All: |
12 reference(s)
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Analysis Tools
