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| Nomenclature |
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Symbol:
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Cox10tm1Ctm
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Name:
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cytochrome c oxidase assembly protein 10;
targeted mutation 1, Carlos T Moraes
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MGI ID: |
MGI:3605782 |
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Synonyms: |
COX10Flx |
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Gene:
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Cox10
Location:
Chr11:63962627-64079468 bp, - strand
Genetic Position: Chr11,
39.47 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101747
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: LoxP sites were inserted to flank exon 6. This exon is homologous to sequence encoding part of the active site of the bacterial enzyme. (J:101747)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Cox10 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:101747
Diaz F et al.,
"Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency."
Hum Mol Genet 2005 Sep 15;14(18):2737-48
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All: |
8 reference(s)
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Analysis Tools
