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| Nomenclature |
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Symbol:
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Asltm1Wjc
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Name:
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argininosuccinate lyase;
targeted mutation 1, William J Craigen
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MGI ID: |
MGI:3604881 |
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Synonyms: |
AL- |
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Gene:
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Asl
Location:
Chr5:130011258-130025132 bp, - strand
Genetic Position: Chr5,
68.37 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101658
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Parent Cell Line:
| AB2.2 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 8 and 9 were replaced with a neomycin resistance cassette, creating an out of frame transcript beginning at exon 10. (J:101658)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Asl Mutation:
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1 strain or line available |
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| References |
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Original: |
J:101658
Reid Sutton V et al.,
"A mouse model of argininosuccinic aciduria: biochemical characterization."
Mol Genet Metab 2003 Jan;78(1):11-6
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All: |
2 reference(s)
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Analysis Tools
