|
|
| Nomenclature |
|
Symbol:
|
Sgcetm1Ygl
|
|
Name:
|
sarcoglycan, epsilon;
targeted mutation 1, Yuqing Li
|
|
MGI ID: |
MGI:3604206 |
|
Gene:
|
Sgce
Location:
Chr6:4674350-4747204 bp, - strand
Genetic Position: Chr6,
1.81 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:101332
|
|
Parent Cell Line:
| D3 (ES Cell) |
|
Strain of Origin:
|
129S2/SvPas
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutation: | |
Intragenic deletion |
| |
|
Mutation details: Exon 4 was deleted via cre mediated recombination. RT-PCR analysis failed to detect mRNA from mutant brain samples. Deletion of exon 4 would cause a frame shift and create a premature stop codon in exon 5 when splicing occurs between exons 3 and 5. (J:101332)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Sgce Mutation:
|
19 strains or lines available |
|
|
Notes |
This allele is maternally imprinted.
|
| References |
|
Original: |
J:101332
Yokoi F et al.,
"Exclusive paternal expression and novel alternatively spliced variants of epsilon-sarcoglycan mRNA in mouse brain."
FEBS Lett 2005 Aug 29;579(21):4822-8
|
|
All: |
4 reference(s)
|
|
Analysis Tools
