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| Nomenclature |
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Symbol:
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Tg(Plp1-SNCA)1Haa
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Name:
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transgene insertion 1, Christian Haass
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MGI ID: |
MGI:3604008 |
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Transgene:
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Tg(Plp1-SNCA)1Haa
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x DBA/2)
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: The proteolipid protein promoter was used to drive human wild-type alpha synuclein expression. Transgenic protein was detected in oligodendrocytes but in no other brain cell type. Lines 5, 25 and 27 were also created. (J:100960)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:100960
Kahle PJ et al.,
"Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes."
EMBO Rep 2002 Jun;3(6):583-8
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All: |
5 reference(s)
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Analysis Tools
