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| Nomenclature |
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Symbol:
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Neurod1tm1Kan
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Name:
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neurogenic differentiation 1;
targeted mutation 1, Klaus-Armin Nave
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MGI ID: |
MGI:3603334 |
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Synonyms: |
Neurod1f, NeuroDloxP(neoTk) |
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Gene:
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Neurod1
Location:
Chr2:79452521-79456751 bp, - strand
Genetic Position: Chr2,
47.58 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:101098
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Parent Cell Line:
| E14.1 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo was inserted into intron 1 and a third loxP site was inserted in the 3' UTR. RT-PCR and Northern blot confirmed aberrant splicing of exon 1 to the neo cassette, creating a nonfunctional allele. (J:101098)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Neurod1 Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:101098
Goebbels S et al.,
"Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2."
Genesis 2005 Aug;42(4):247-52
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All: |
2 reference(s)
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Analysis Tools
