|
|
| Nomenclature |
|
Symbol:
|
Syngap1tm1.2Mabk
|
|
Name:
|
synaptic Ras GTPase activating protein 1 homolog (rat);
targeted mutation 1.2, Mary B Kennedy
|
|
MGI ID: |
MGI:3603311 |
|
Synonyms: |
synGAP flox |
|
Gene:
|
Syngap1
Location:
Chr17:26941452-26970645 bp, + strand
Genetic Position: Chr17,
13.6 cM
|
|
Mutation origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:101084
|
|
Parent Cell Line:
| CJ7 (ES Cell) |
|
Strain of Origin:
|
129S1/Sv-Oca2+ Tyr+ Kitl+
|
|
Mutation description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Exons 4 and 9 remained flanked with loxP sites after the removal of a floxed neo cassette. (J:101084)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:101084
Knuesel I et al.,
"A role for synGAP in regulating neuronal apoptosis."
Eur J Neurosci 2005 Feb;21(3):611-21
|
|
All: |
1 reference(s)
|
|