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| Nomenclature |
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Symbol:
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CrygbClapper
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Name:
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crystallin, gamma B;
Clapper
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MGI ID: |
MGI:3590646 |
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Synonyms: |
gammaB-I4F, L10 |
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Gene:
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Crygb
Location:
Chr1:65080228-65082267 bp, - strand
Genetic Position: Chr1,
32.82 cM
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Cataracts in CrygbClapper/CrygbClapper and CrygbClapper/Crygb+ mice
Show the 2 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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C57BL/6J
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: This allele contains an A to T missense mutation that replaces the conserved fourth isoleucine residue with a phenylalanine. (J:100851)
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Inheritance: | |
Dominant |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:100851
Liu H et al.,
"Crystallin {gamma}B-I4F mutant protein binds to {alpha}-crystallin and affects lens transparency."
J Biol Chem 2005 Jul 1;280(26):25071-8
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All: |
2 reference(s)
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Analysis Tools
