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| Nomenclature |
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Symbol:
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Col8a2tm1Bjro
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Name:
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collagen, type VIII, alpha 2;
targeted mutation 1, Bjorn R Olsen
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MGI ID: |
MGI:3587617 |
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Synonyms: |
Col8a2- |
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Gene:
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Col8a2
Location:
Chr4:126286793-126314330 bp, + strand
Genetic Position: Chr4,
60.29 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100136
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: A PGK driven neomycin resistance gene was inserted into exon 1. Northern blot of mutants detected no transcripts. (J:100136)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Col8a2 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:100136
Hopfer U et al.,
"Targeted disruption of Col8a1 and Col8a2 genes in mice leads to anterior segment abnormalities in the eye."
FASEB J 2005 Aug;19(10):1232-44
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All: |
4 reference(s)
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Analysis Tools
