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| Nomenclature |
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Symbol:
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Zfpm2lil
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Name:
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zinc finger protein, multitype 2;
little lung
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MGI ID: |
MGI:3587413 |
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Synonyms: |
Fog2lil, lil |
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Gene:
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Zfpm2
Location:
Chr15:40655042-41104592 bp, + strand
Genetic Position: Chr15,
15.74 cM, cytoband C
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Abnormal pulmonary and diaphragmatic development in the Zfpm2lil/Zfpm2lil mouse
Show the 1 image(s) involving this allele.
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Mutation
origin |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Chemically induced (ENU) |
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Mutation: | |
Single point mutation |
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Mutation details: A C to T transition 2 bp after position 301, the splice donor site at the end of exon 3, caused a splicing defect resulting in the insertion of 85 bp of intronic sequence into the transcript and introduces a stop codon that generates a severely truncated protein. (J:100119)
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Inheritance: | |
Not Specified |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Zfpm2 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:100119
Ackerman KG et al.,
"Fog2 is required for normal diaphragm and lung development in mice and humans."
PLoS Genet 2005 Jul;1(1):e10
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All: |
1 reference(s)
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Analysis Tools
