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| Nomenclature |
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Symbol:
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Ndntm1Ky
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Name:
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necdin;
targeted mutation 1, Kazuaki Yoshikawa
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MGI ID: |
MGI:3586988 |
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Synonyms: |
Ndn- |
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Gene:
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Ndn
Location:
Chr7:62348277-62349928 bp, + strand
Genetic Position: Chr7,
34.36 cM, cytoband C
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100024
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: The insetion of a PGK-neo into the coding sequence disrupted the locus. Western blot of mutants showed absence of protein. (J:100024)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:100024
Kuwako K et al.,
"Disruption of the paternal necdin gene diminishes TrkA signaling for sensory neuron survival."
J Neurosci 2005 Jul 27;25(30):7090-9
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All: |
7 reference(s)
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Analysis Tools
