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| Nomenclature |
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Symbol:
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Fem1btm1Jfma
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Name:
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feminization 1 homolog b (C. elegans);
targeted mutation 1, Joseph F Maher
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MGI ID: |
MGI:3586916 |
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Synonyms: |
Fem1b- |
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Gene:
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Fem1b
Location:
Chr9:62791832-62811648 bp, - strand
Genetic Position: Chr9,
33.87 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100017
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: A PGK-neo cassette replaced the first exon, which contains the translation initiation codon and the first two ankyrin repeats. Northern blot from mutant testis confirmed absence of transcript and Western blot of mutant brain showed absence of protein. (J:100017)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fem1b Mutation:
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9 strains or lines available |
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| References |
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Original: |
J:100017
Lu D et al.,
"Abnormal glucose homeostasis and pancreatic islet function in mice with inactivation of the fem1b gene."
Mol Cell Biol 2005 Aug;25(15):6570-7
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All: |
1 reference(s)
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Analysis Tools
