|
|
| Nomenclature |
|
Symbol:
|
Igk-Jtm1Mcdl
|
|
Name:
|
immunoglobulin kappa chain, joining region;
targeted mutation 1, Maria A Curotto de Lafaille
|
|
MGI ID: |
MGI:3586522 |
|
Gene:
|
Igk-J
Location:
unknown
Genetic Position: Chr6,
Syntenic
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:100072
|
|
Parent Cell Line:
| J1 (ES Cell) |
|
Strain of Origin:
|
129S4/SvJae
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-in) |
|
Mutation: | |
Insertion |
| |
|
All five heavy chain J elements were replaced with a rearranged V(D)J region. (J:100072)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Igk-J Mutation:
|
7 strains or lines available |
|
| References |
|
Original: |
J:100072
Curotto de Lafaille MA et al.,
"Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes."
J Exp Med 2001 Nov 5;194(9):1349-59
|
|
All: |
5 reference(s)
|
|
Analysis Tools
