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| Nomenclature |
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Symbol:
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Igh-Jtm1Mcdl
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Name:
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immunoglobulin heavy chain, joining region;
targeted mutation 1, Maria A Curotto de Lafaille
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MGI ID: |
MGI:3586521 |
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Gene:
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Igh-J
Location:
unknown
Genetic Position: Chr12,
Syntenic
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:100072
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Parent Cell Line:
| J1 (ES Cell) |
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Strain of Origin:
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129S4/SvJae
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutations: | |
Insertion, Intergenic deletion |
| |
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DQ52 and all four heavy chain J elements were replaced by a rearranged V(D)J region. (J:100072)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Igh-J Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:100072
Curotto de Lafaille MA et al.,
"Hyper immunoglobulin E response in mice with monoclonal populations of B and T lymphocytes."
J Exp Med 2001 Nov 5;194(9):1349-59
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All: |
5 reference(s)
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Analysis Tools
