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| Nomenclature |
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Symbol:
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Tg(tetO-Vegfa)90Ala
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Name:
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transgene insertion 90, Ann L Akeson
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MGI ID: |
MGI:3586336 |
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Synonyms: |
(tetO)7VEGF, (tetO)7VEGF164+, tetOVEGF164 |
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Transgene:
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Tg(tetO-Vegfa)90Ala
Location:
unknown
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Transgene origin |
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Transgene description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: This transgene contains cDNA for the murine Vegfa isoform VEGF-A164 which was inserted between seven copies of the tetracycline Operator (tetO)7-CMV minimal promoter and the bovine growth factor polyadenylation signals sequence. TetO, when present in cells also carrying a tetracycline transactivator (tTA) or reverse transactivator (rtTA) transgene, is inactivated or activated, respectively, by the administration of tetracycline or its analogue doxycycline. (J:86840)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:86840
Akeson AL et al.,
"Temporal and spatial regulation of VEGF-A controls vascular patterning in the embryonic lung."
Dev Biol 2003 Dec 15;264(2):443-55
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All: |
13 reference(s)
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