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| Nomenclature |
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Symbol:
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Rdh8tm1Kpal
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Name:
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retinol dehydrogenase 8;
targeted mutation 1, Krzysztof Palczewski
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MGI ID: |
MGI:3586327 |
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Synonyms: |
prRDH- |
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Gene:
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Rdh8
Location:
Chr9:20818504-20826163 bp, + strand
Genetic Position: Chr9,
7.64 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:99930
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 2-4 were replaced with a neomycin resistance gene. Immunoblot of mutants confirmed absence of protein. (J:99930)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Rdh8 Mutation:
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1 strain or line available |
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| References |
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Original: |
J:99930
Maeda A et al.,
"Role of photoreceptor-specific retinol dehydrogenase in the retinoid cycle in vivo."
J Biol Chem 2005 May 13;280(19):18822-32
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All: |
14 reference(s)
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Analysis Tools
