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| Nomenclature |
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Symbol:
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Csf2tm1Dran
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Name:
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colony stimulating factor 2 (granulocyte-macrophage);
targeted mutation 1, Glen Dranoff
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MGI ID: |
MGI:3586299 |
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Synonyms: |
GM-CSF - |
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Gene:
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Csf2
Location:
Chr11:54247271-54249667 bp, - strand
Genetic Position: Chr11,
32.13 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:67404
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Parent Cell Line:
| D3 (ES Cell) |
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Strain of Origin:
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129S2/SvPas
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A hygromycin resistance cassette replaced exons 3 and 4 in an ES cell line in which the Il3 gene had already been targeted (MGI:2446538). Absence of protein was demonstrated immunologically. (J:67404)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Csf2 Mutation:
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11 strains or lines available |
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| References |
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Original: |
J:67404
Gillessen S et al.,
"Overlapping roles for granulocyte-macrophage colony-stimulating factor and interleukin-3 in eosinophil homeostasis and contact hypersensitivity."
Blood 2001 Feb 15;97(4):922-8
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All: |
8 reference(s)
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Analysis Tools
