|
|
| Nomenclature |
|
Symbol:
|
Foxp2tm1Bux
|
|
Name:
|
forkhead box P2;
targeted mutation 1, Joseph D Buxbaum
|
|
MGI ID: |
MGI:3584266 |
|
Synonyms: |
Foxp2- |
|
Gene:
|
Foxp2
Location:
Chr6:14901388-15441201 bp, + strand
Genetic Position: Chr6,
6.49 cM, cytoband A2
|
|
Histological analysis of brains of Foxp2tm1Bux and wild type mice
Show the 1 image(s) involving this allele.
|
 |
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:99864
|
|
Parent Cell Line:
| Not Specified (ES Cell) |
|
Strain of Origin:
|
Not Specified
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (knock-out) |
|
Mutations: | |
Insertion, Intragenic deletion |
| |
|
Mutation details: A neomycin resistance cassette replaced exons 12 and 13. Northern blot failed to detect transcript in mutants and immunoblot further confirmed successful targeting. (J:99864)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
Carrying any Foxp2 Mutation:
|
2 strains or lines available |
|
| References |
|
Original: |
J:99864
Shu W et al.,
"Altered ultrasonic vocalization in mice with a disruption in the Foxp2 gene."
Proc Natl Acad Sci U S A 2005 Jul 5;102(27):9643-8
|
|
All: |
2 reference(s)
|
|
Analysis Tools
