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| Nomenclature |
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Symbol:
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Ttltm1Wehl
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Name:
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tubulin tyrosine ligase;
targeted mutation 1, Juergen Wehland
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MGI ID: |
MGI:3584264 |
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Synonyms: |
TTL- |
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Gene:
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Ttl
Location:
Chr2:129065942-129096283 bp, + strand
Genetic Position: Chr2,
62.65 cM, cytoband F3
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:99877
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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A PGK-neo cassette replaced exon 1. Western blot failed to detect protein in mutants. (J:99877)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Ttl Mutation:
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3 strains or lines available |
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| References |
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Original: |
J:99877
Erck C et al.,
"A vital role of tubulin-tyrosine-ligase for neuronal organization."
Proc Natl Acad Sci U S A 2005 May 31;102(22):7853-8
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All: |
5 reference(s)
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