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Ttltm1Wehl
Targeted Allele Detail

Nomenclature
Symbol: Ttltm1Wehl
Name: tubulin tyrosine ligase; targeted mutation 1, Juergen Wehland
MGI ID: MGI:3584264
Synonyms: TTL-
Gene: Ttl   Location: Chr2:129065942-129096283 bp, + strand    Genetic Position: Chr2, 62.65 cM, cytoband F3
Mutation
origin
Germline Transmission: Earliest citation of germline transmission: J:99877
Parent Cell Line: R1 (ES Cell)
Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:   Targeted (knock-out)
Mutations:   Insertion, Intragenic deletion
    A PGK-neo cassette replaced exon 1. Western blot failed to detect protein in mutants. (J:99877)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR) Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation: Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ttl Mutation: 3 strains or lines available
References
Original: J:99877 Erck C et al., "A vital role of tubulin-tyrosine-ligase for neuronal organization." Proc Natl Acad Sci U S A 2005 May 31;102(22):7853-8
All: 5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
05/08/2013
MGI 5.13
The Jackson Laboratory