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| Nomenclature |
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Symbol:
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Tg(TcraTcrbNY8.3)1Pesa
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Name:
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transgene insertion 1, Pere Santamaria
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MGI ID: |
MGI:3584121 |
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Synonyms: |
8.3TCR, 8.3-TCR, 8.3-TCR-alpha/beta transgene, 8.3-TCR-TG, NY8.3, Tcr8.3 |
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Transgene:
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Tg(TcraTcrbNY8.3)1Pesa
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(SJL x C57BL/6)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: Functional VDJbeta and VJalpha rearrangements were isolated from the beta cell cytotoxic CD8(+) T cell clone NY8.3. Upstream regualtory sequence together with either TCR-beta enhancers or TCR-alpha enhancers, as appropriate, were associated with VDJbeta or VJalpha. (J:44202)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:44202
Verdaguer J et al.,
"Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice."
J Exp Med 1997 Nov 17;186(10):1663-76
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All: |
37 reference(s)
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Analysis Tools
