|
|
| Nomenclature |
|
Symbol:
|
Tg(Col2a1-PTHR1*H223R)AHju
|
|
Name:
|
transgene insertion A, Harald Juppner
|
|
MGI ID: |
MGI:3584013 |
|
Synonyms: |
CaPpr, Tg-A |
|
Transgene:
|
Tg(Col2a1-PTHR1*H223R)AHju
Location:
unknown
|
|
Skeletal images of wild-type and Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju mice
Show the 5 image(s) involving this allele.
|
 |
|
Transgene
origin |
|
Strain of Origin:
|
C57BL/6
|
|
Transgene
description |
|
Transgene
Type: | |
Transgenic (random, expressed) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: A 1,880-bp cDNA fragment encoding the constitutively active human PTHR1 containing an H223R mutation (HKrk-H223R) was placed downstream of the rat alpha (II) collagen promoter. The A line contains only one copy of the transgene. (J:77639)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
|
| References |
|
Original: |
J:77639
Schipani E et al.,
"Targeted expression of constitutively active receptors for parathyroid hormone and parathyroid hormone-related peptide delays endochondral bone formation and rescues mice that lack parathyroid hormone-related peptide."
Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94
|
|
All: |
7 reference(s)
|
|
Analysis Tools
