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| Nomenclature |
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Symbol:
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Tg(Upk2-cre)6Xrw
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Name:
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transgene insertion 6, Xue-Ru Wu
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MGI ID: |
MGI:3583893 |
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Synonyms: |
Tg(Upk1b-cre)6Xrw, UPII-Cre |
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Transgene:
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Tg(Upk2-cre)6Xrw
Location:
unknown
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Transgene
origin |
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: A construct was generated having a 3.6 kb fragment of the mouse Upk2 promoter, cre recombinase and a polyA signal. The transgene was purified and microinjected into fertilized FVB/N oocytes. Three founder lines 4,5,6) were obtained, all showing germline transmission and urothelium-specific cre mRNA expression (not detected in any other tissues). Mice established from founder 6 were crossed to reporter mice to verify cre recombinase activity in the urothelium. (J:99613)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:99613
Mo L et al.,
"Gene deletion in urothelium by specific expression of Cre recombinase"
Am J Physiol Renal Physiol 2005 Sep;289(3):F562-8
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All: |
4 reference(s)
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Analysis Tools
