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| Nomenclature |
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Symbol:
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Mafatm1Staka
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Name:
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v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian);
targeted mutation 1, Satoru Takahashi
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MGI ID: |
MGI:3581892 |
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Synonyms: |
MafA- |
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Gene:
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Mafa
Location:
Chr15:75746843-75747922 bp, - strand
Genetic Position: Chr15,
34.82 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:99126
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An NLS-lacZ-neo cassette replaced sequences encoding both the transactivation and basic motif-leucine zipper domains. Beta-galactosidase expression was observed in the lens, somites and olfactory bulb, as well as pancreateic islets. (J:99126)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:99126
Zhang C et al.,
"MafA is a key regulator of glucose-stimulated insulin secretion."
Mol Cell Biol 2005 Jun;25(12):4969-76
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All: |
5 reference(s)
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Analysis Tools
