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| Nomenclature |
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Symbol:
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Tg(Tyr-cre)3Gfk
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Name:
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transgene insertion 3, Graham F Kay
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MGI ID: |
MGI:3580525 |
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Synonyms: |
TEC3, TgN(TyrCre)3Gfk |
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Transgene:
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Tg(Tyr-cre)3Gfk
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6 x CBA)F2 or (C57BL/6 x 129)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (Cre/Flp) |
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Mutation: | |
Insertion |
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Mutation details: These transgenes express cre under the control of the tyrosinase promoter. Three lines were reported. Lines 1 and 2 include the full enhancer in addition to the promoter. Line 3 lacks the enhancer. Line 3 expresses cre soley in melanoblasts. (J:87271)
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Recombinase activity
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Notes |
Strain of origin for these mtransgenes is either BCBF2 or B6129F2. They were subsequently backcrossed to C57BL/6 for maintainance.
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| References |
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Original: |
J:87271
Tonks ID et al.,
"Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues."
Genesis 2003 Nov;37(3):131-8
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All: |
3 reference(s)
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Analysis Tools
