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| Nomenclature |
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Symbol:
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Itgadtm1Bll
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Name:
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integrin, alpha D;
targeted mutation 1, Christie M Ballantyne
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MGI ID: |
MGI:3579559 |
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Synonyms: |
CD11d- |
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Gene:
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Itgad
Location:
Chr7:128154376-128223816 bp, + strand
Genetic Position: Chr7,
70.0 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:90954
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Parent Cell Line:
| AB2.1 (ES Cell) |
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Strain of Origin:
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129S7/SvEvBrd-Hprtb-m2
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A 2.2 kb genomic fragment containing exons 1 and 2 were replaced with a neomycin selection cassette. Flow cytometry demonstrated the absence of protein expression in splenocytes. (J:90954)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:90954
Wu H et al.,
"Deficiency of CD11b or CD11d results in reduced staphylococcal enterotoxin-induced T cell response and T cell phenotypic changes."
J Immunol 2004 Jul 1;173(1):297-306
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All: |
2 reference(s)
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Analysis Tools
