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| Nomenclature |
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Symbol:
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Fkbp4tm1Dvds
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Name:
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FK506 binding protein 4;
targeted mutation 1, David F Smith
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MGI ID: |
MGI:3579432 |
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Synonyms: |
52KO, Fkbp52- |
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Gene:
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Fkbp4
Location:
Chr6:128429735-128438677 bp, - strand
Genetic Position: Chr6,
63.0 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:98554
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A neomycin resistance gene replaced the entire coding sequence. Western blot failed to detect protein in thymic cytosol of mutants. (J:98554)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:98554
Cheung-Flynn J et al.,
"Physiological role for the cochaperone FKBP52 in androgen receptor signaling."
Mol Endocrinol 2005 Jun;19(6):1654-66
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All: |
7 reference(s)
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