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| Nomenclature |
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Symbol:
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Irf8myls
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Name:
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interferon regulatory factor 8;
myeloproliferative syndrome
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MGI ID: |
MGI:3578920 |
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Synonyms: |
Icsbp1C294, IRF-8C294, Irf8R294C |
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Gene:
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Irf8
Location:
Chr8:120736358-120756694 bp, + strand
Genetic Position: Chr8,
70.05 cM
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Mutation
origin |
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Strain of Origin:
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BXH2/TyJ
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Mutation
description |
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Allele
Type: | |
Spontaneous |
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Mutation: | |
Single point mutation |
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Mutation details: Sequencing revealed a C to T transition at position 915 of cDNA, creating an R294C substitution within the putative IAD domain. (J:97931)
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Inheritance: | |
Recessive |
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Irf8 Mutation:
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4 strains or lines available |
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| References |
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Original: |
J:88564
Turcotte K et al.,
"Genetic control of myeloproliferation in BXH-2 mice."
Blood 2004 Mar 15;103(6):2343-50
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All: |
11 reference(s)
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Analysis Tools
