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| Nomenclature |
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Symbol:
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Festm2Pag
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Name:
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feline sarcoma oncogene;
targeted mutation 2, Peter A Greer
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MGI ID: |
MGI:3578748 |
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Synonyms: |
fps- |
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Gene:
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Fes
Location:
Chr7:80377758-80387946 bp, - strand
Genetic Position: Chr7,
45.65 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:98590
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
| |
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Exons 15 through 18 were replaced with a PGKneo cassette via homologous recombination. (J:98590)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Fes Mutation:
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1 strain or line available |
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| References |
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Original: |
J:98590
Zirngibl RA et al.,
"Enhanced endotoxin sensitivity in fps/fes-null mice with minimal defects in hematopoietic homeostasis."
Mol Cell Biol 2002 Apr;22(8):2472-86
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All: |
8 reference(s)
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Analysis Tools
