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| Nomenclature |
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Symbol:
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Plxna4tm1Hfu
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Name:
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plexin A4;
targeted mutation 1, Hajime Fujisawa
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MGI ID: |
MGI:3578655 |
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Synonyms: |
PlxnA4- |
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Gene:
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Plxna4
Location:
Chr6:32145926-32588192 bp, - strand
Genetic Position: Chr6,
12.9 cM, cytoband B1
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:98330
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Most of the exon, including the coding region for the sema domain, was deleted upon the insertion of a loxP-IRES Tak PGK-neo cassette. Western blot confirmed that mutants have the null allele. (J:98330)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:98330
Suto F et al.,
"Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance."
J Neurosci 2005 Apr 6;25(14):3628-37
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All: |
7 reference(s)
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Analysis Tools
