|
|
| Nomenclature |
|
Symbol:
|
Spry2tm1Mrt
|
|
Name:
|
sprouty homolog 2 (Drosophila);
targeted mutation 1, Gail R Martin
|
|
MGI ID: |
MGI:3578632 |
|
Synonyms: |
Spry2fl, Spry2flox |
|
Gene:
|
Spry2
Location:
Chr14:105891949-105896819 bp, - strand
Genetic Position: Chr14,
56.16 cM
|
|
Mutation
origin |
|
Germline Transmission:
|
Earliest citation of germline transmission:
J:98303
|
|
Parent Cell Line:
| E14TG2a.4 (ES Cell) |
|
Strain of Origin:
|
129P2/OlaHsd
|
|
Mutation
description |
|
Allele
Type: | |
Targeted (Floxed/Frt) |
|
Mutation: | |
Insertion |
| |
|
Mutation details: An frt-flanked neo was inserted immediately upstream of the ORF and loxP sites were inserted to flank the ORF. Crossing with mice expressing FLP recombinase removed the neo. (J:98303)
|
|
Phenotypes
|
View phenotypes for all genotypes (concatenated display).
|
|
Disease models
|
|
| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
|
| References |
|
Original: |
J:98303
Shim K et al.,
"Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling."
Dev Cell 2005 Apr;8(4):553-64
|
|
All: |
14 reference(s)
|
|
Analysis Tools
