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| Nomenclature |
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Symbol:
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Jag1tm1Frad
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Name:
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jagged 1;
targeted mutation 1, Freddy Radtke
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MGI ID: |
MGI:3577993 |
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Synonyms: |
J1lox |
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Gene:
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Jag1
Location:
Chr2:137081456-137116644 bp, - strand
Genetic Position: Chr2,
67.73 cM
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Mutation origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:98129
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Parent Cell Line:
| GS1 (ES Cell) |
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Strain of Origin:
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129/Sv
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Mutation description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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LoxP sites were inserted to flank the first two coding exons. (J:98129)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Jag1 Mutation:
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7 strains or lines available |
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| References |
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Original: |
J:98129
Mancini SJ et al.,
"Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation."
Blood 2005 Mar 15;105(6):2340-2
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All: |
4 reference(s)
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