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| Nomenclature |
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Symbol:
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Tgif1tm1.1Caw
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Name:
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TGFB-induced factor homeobox 1;
targeted mutation 1.1, Christopher A Walsh
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MGI ID: |
MGI:3577049 |
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Synonyms: |
Tgif- |
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Gene:
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Tgif1
Location:
Chr17:70844205-70853546 bp, - strand
Genetic Position: Chr17,
41.87 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:97642
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Tgiftm1Caw mice were crossed with mice expressing cre in the germline to produce this allele in which exons 2 and 3 are deleted. Western blot demonstrated lack of protein in mutant embryos. (J:97642)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Tgif1 Mutation:
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32 strains or lines available |
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| References |
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Original: |
J:97642
Shen J et al.,
"Targeted disruption of tgif, the mouse ortholog of a human holoprosencephaly gene, does not result in holoprosencephaly in mice."
Mol Cell Biol 2005 May;25(9):3639-47
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All: |
1 reference(s)
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Analysis Tools
