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| Nomenclature |
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Symbol:
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Angptl6tm1Yo
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Name:
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angiopoietin-like 6;
targeted mutation 1, Yuichi Oike
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MGI ID: |
MGI:3576787 |
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Synonyms: |
AGF- |
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Gene:
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Angptl6
Location:
Chr9:20873809-20879727 bp, - strand
Genetic Position: Chr9,
7.66 cM, cytoband A3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:97552
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A PGK-neo was inserted to replace the 5' UTR. Northern blot and Western blot demonstrated lack of transcript and protein, respectively, in mutants. (J:97552)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Angptl6 Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:97552
Oike Y et al.,
"Angiopoietin-related growth factor antagonizes obesity and insulin resistance."
Nat Med 2005 Apr;11(4):400-8
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All: |
1 reference(s)
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Analysis Tools
