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| Nomenclature |
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Symbol:
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Ehmt1tm1Yshk
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Name:
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euchromatic histone methyltransferase 1;
targeted mutation 1, Yoichi Shinkai
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MGI ID: |
MGI:3575505 |
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Synonyms: |
GLP- |
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Gene:
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Ehmt1
Location:
Chr2:24790769-24919609 bp, - strand
Genetic Position: Chr2,
16.73 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:97244
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Parent Cell Line:
| TT2 (ES Cell) |
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Strain of Origin:
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(C57BL/6NCrlj x CBA/JNCrlj)F1
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A targeting vector was designed to replace exon 5 and part of exon 6 with a neomycin resistance gene. The deleted sequence encodes the catalytic core region of the SET domain. (J:97244)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:97244
Tachibana M et al.,
"Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9."
Genes Dev 2005 Apr 1;19(7):815-26
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All: |
3 reference(s)
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Analysis Tools
