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| Nomenclature |
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Symbol:
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Umodtm1Kuma
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Name:
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uromodulin;
targeted mutation 1, Satish Kumar
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MGI ID: |
MGI:3574985 |
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Synonyms: |
THP- |
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Gene:
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Umod
Location:
Chr7:119462866-119479255 bp, - strand
Genetic Position: Chr7,
63.88 cM, cytoband F1-F2
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:97228
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Insertion |
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Mutation details: The insertion of a neo interrupted the coding sequence in exon 2. Northern and Western blot as well as immunocytochemistry confirmed absence of transcript and protein in mutant mice. (J:97228)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Umod Mutation:
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1 strain or line available |
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| References |
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Original: |
J:97228
Bates JM et al.,
"Tamm-Horsfall protein knockout mice are more prone to urinary tract infection: rapid communication."
Kidney Int 2004 Mar;65(3):791-7
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All: |
4 reference(s)
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Analysis Tools
