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| Nomenclature |
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Symbol:
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Lmo4tm1.1Gng
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Name:
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LIM domain only 4;
targeted mutation 1.1, Gordon N Gill
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MGI ID: |
MGI:3574586 |
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Synonyms: |
Lmo4- |
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Gene:
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Lmo4
Location:
Chr3:144188530-144205220 bp, - strand
Genetic Position: Chr3,
68.61 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:96957
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129X1/SvJ
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutation: | |
Intragenic deletion |
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Mutation details: Exons 1b and 2 were removed via cre-mediated recombination. This sequence contains the translation start site and N-terminal LIM domain. Immunohistochemical staining confirmed absence of protein in cervical spinal cord sections of mutants. (J:96957)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Lmo4 Mutation:
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6 strains or lines available |
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| References |
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Original: |
J:96957
Lee SK et al.,
"The LIM domain-only protein LMO4 is required for neural tube closure."
Mol Cell Neurosci 2005 Feb;28(2):205-14
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All: |
4 reference(s)
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Analysis Tools
