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| Nomenclature |
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Symbol:
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Dclre1ctm2Mcow
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Name:
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DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae);
targeted mutation 2, Morton J Cowan
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MGI ID: |
MGI:3574021 |
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Synonyms: |
mArt- |
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Gene:
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Dclre1c
Location:
Chr2:3424131-3464130 bp, + strand
Genetic Position: Chr2,
1.93 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:96535
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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129
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: Exons 6-11, encompassing 80% of the gene, were replaced with a neo. Western blot of lymphoid tissues demonstrated the lack of wild-type protein in mutants. (J:96535)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:96535
Li L et al.,
"Targeted disruption of the artemis murine counterpart results in SCID and defective V(D)J recombination that is partially corrected with bone marrow transplantation."
J Immunol 2005 Feb 15;174(4):2420-8
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All: |
1 reference(s)
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Analysis Tools
