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| Nomenclature |
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Symbol:
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Tg(SOD1*G37R)9Dpr
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Name:
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transgene insertion 9, Donald L Price
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MGI ID: |
MGI:3574015 |
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Synonyms: |
Tg(SOD1-G37R)9Dpr |
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Transgene:
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Tg(SOD1*G37R)9Dpr
Location:
unknown
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Transgene
origin |
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Strain of Origin:
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(C57BL/6J x C3H/HeJ)F2
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Transgene
description |
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Transgene
Type: | |
Transgenic (random, expressed) |
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Mutation: | |
Insertion |
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Mutation details: A 12 kb genomic DNA fragment containing a mutated form of human SOD1 with a glycine to arginine substitution at amino acid 37 (G37R) was used for the transgene. The G37R mutation is found in some cases of familial amyotrophic lateral sclerosis (FALS). (J:69178)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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| References |
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Original: |
J:69178
Wong PC et al.,
"An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria."
Neuron 1995 Jun;14(6):1105-16
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All: |
2 reference(s)
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Analysis Tools
