Pax3tm1(cre)Joe
Targeted Allele Detail
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| Nomenclature |
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Symbol:
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Pax3tm1(cre)Joe
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Name:
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paired box gene 3;
targeted mutation 1, Jonathan A Epstein
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MGI ID: |
MGI:3573783 |
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Synonyms: |
Pax3Cre, Pax3-Cre, Pax3Cre-KI |
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Gene:
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Pax3
Location:
Chr1:78101267-78197134 bp, - strand
Genetic Position: Chr1,
39.79 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:96431
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-in) |
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Mutation: | |
Insertion |
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Mutation details: A targeting vector was desinged to insert the cre recombinase cDNA followed by a stop codon and a polyA signal in place of exon 1 of the endogenous locus. (J:96431)
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Recombinase activity
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Activity in:
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adipose tissue,
alimentary system,
branchial arches,
cardiovascular system,
cavities & their linings,
embryo-other,
endocrine system,
hemolymphoid system,
integumental system,
limbs,
mesenchyme,
muscle,
nervous system,
postnatal-other,
renal & urinary system,
reproductive system,
respiratory system,
sensory organs,
skeletal system,
tail
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Not detected in:
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liver & biliary system
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Driver:
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Pax3
Summary of all recombinase alleles
driven by Pax3.
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:96431
Lang D et al.,
"Pax3 functions at a nodal point in melanocyte stem cell differentiation."
Nature 2005 Feb 24;433(7028):884-7
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All: |
42 reference(s)
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Analysis Tools
