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| Nomenclature |
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Symbol:
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Phox2a/Inppl1tm1Ssch
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Name:
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paired-like homeobox 2a;
targeted mutation 1, Stephane Schurmans
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MGI ID: |
MGI:3531321 |
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Synonyms: |
SHIP2- |
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Gene:
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Phox2a
Location:
Chr7:101818313-101823166 bp, + strand
Genetic Position: Chr7,
54.66 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:96443
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Parent Cell Line:
| R1 (ES Cell) |
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Strain of Origin:
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(129X1/SvJ x 129S1/Sv)F1-Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intergenic deletion |
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Mutation details: 7.3 kb genomic sequence containing C-terminal of two genes, Inppl1 and Phox2a were disrupted by the integration of a single targeting construct. A neomycin selection cassette replaced sequence extending from Inppl1 (exons 19-29) and Phox2a (exon 3). (J:96443)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Phox2a Mutation:
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5 strains or lines available |
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| References |
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Original: |
J:96443
Clement S et al.,
"The lipid phosphatase SHIP2 controls insulin sensitivity. (Erratum: Nature 2004 Oct 14;4131(7010):878)"
Nature 2001 Jan 4;409(6816):92-7
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All: |
1 reference(s)
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Analysis Tools
