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| Nomenclature |
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Symbol:
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Kiss1rtm1Coll
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Name:
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KISS1 receptor;
targeted mutation 1, William H Colledge
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MGI ID: |
MGI:3530566 |
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Synonyms: |
gpr54-, Gpr54tm1Par, Gpr54tm1PTL |
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Gene:
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Kiss1r
Location:
Chr10:79916971-79922273 bp, + strand
Genetic Position: Chr10,
39.72 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:96442
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (knock-out) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: An IRES-Betagal-MC-neo cassette was inserted into exon 1, replacing the 3' end of exon 1, intron 1 and the 5' end of exon 2. The deleted sequence encoded transmembrane loops 1 and 2 and the encompassing domains. RT-PCR confirmed that the resulting allele was a null. (J:96442)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Kiss1r Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:96442
Seminara SB et al.,
"The GPR54 gene as a regulator of puberty."
N Engl J Med 2003 Oct 23;349(17):1614-27
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All: |
11 reference(s)
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Analysis Tools
