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| Nomenclature |
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Symbol:
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Frat2tm2Brn
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Name:
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frequently rearranged in advanced T cell lymphomas 2;
targeted mutation 2, Anton Berns
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MGI ID: |
MGI:3530463 |
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Gene:
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Frat2
Location:
Chr19:41845978-41848132 bp, - strand
Genetic Position: Chr19,
35.33 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:96034
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Disruption caused by insertion of vector |
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Mutation details: 635-bp of the coding sequence was replaced by the insertion of a cassette containing a lacZ reporter gene and puromycin selection gene. (J:96034)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Notes |
To generate Frat1/Frat2 double mutant mice, Frat1tm1Brnheterozygous ES cells were targeted with the Frat2 knockout construct.
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| References |
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Original: |
J:96034
van Amerongen R et al.,
"Frat is dispensable for canonical Wnt signaling in mammals."
Genes Dev 2005 Feb 15;19(4):425-30
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All: |
1 reference(s)
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Analysis Tools
