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| Nomenclature |
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Symbol:
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Atrxtm1Pick
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Name:
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alpha thalassemia/mental retardation syndrome X-linked homolog (human);
targeted mutation 1, David J Picketts
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MGI ID: |
MGI:3528480 |
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Synonyms: |
AtrxFl, Atrxflox |
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Gene:
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Atrx
Location:
ChrX:105797615-105929397 bp, - strand
Genetic Position: ChrX,
47.26 cM
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95953
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Parent Cell Line:
| Not Specified (ES Cell) |
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Strain of Origin:
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Not Specified
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Mutation
description |
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Allele
Type: | |
Targeted (Floxed/Frt) |
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Mutation: | |
Insertion |
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Mutation details: A floxed neo was inserted into intron 17 and a loxP sites into intron 18. Excision of this exon would still allow production of the shorter isoform containing exons 1-11. (J:95953)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Atrx Mutation:
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72 strains or lines available |
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| References |
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Original: |
J:95953
Berube NG et al.,
"The chromatin-remodeling protein ATRX is critical for neuronal survival during corticogenesis."
J Clin Invest 2005 Feb;115(2):258-67
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All: |
5 reference(s)
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Analysis Tools
