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| Nomenclature |
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Symbol:
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Sema3etm1Ddg
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Name:
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sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E;
targeted mutation 1, David D Ginty
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MGI ID: |
MGI:3527995 |
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Synonyms: |
sema3e- |
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Gene:
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Sema3e
Location:
Chr5:14025276-14256689 bp, + strand
Genetic Position: Chr5,
5.66 cM
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The vascular network is disorganized in Sema3etm1Ddg/Sema3etm1Ddg retinas
Show the 4 image(s) involving this allele.
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95697
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Parent Cell Line:
| E14 (ES Cell) |
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Strain of Origin:
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129P2/OlaHsd
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutations: | |
Insertion, Intragenic deletion |
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Mutation details: A targeting vector was designed to insert an EGFP and a floxed neo at the start codon, deleting the signal peptide in exon 1. In situ hybridization confirmed the absence of mRNA in mutant mice. (J:95697)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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| References |
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Original: |
J:95697
Gu C et al.,
"Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins."
Science 2005 Jan 14;307(5707):265-8
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All: |
7 reference(s)
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Analysis Tools
