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| Nomenclature |
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Symbol:
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Dok2tm1Ppp
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Name:
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docking protein 2;
targeted mutation 1, Pier Paolo Pandolfi
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MGI ID: |
MGI:3527246 |
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Gene:
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Dok2
Location:
Chr14:70766036-70778495 bp, + strand
Genetic Position: Chr14,
36.71 cM, cytoband D2-D3
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Mutation
origin |
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Germline Transmission:
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Earliest citation of germline transmission:
J:95334
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Parent Cell Line:
| CJ7 (ES Cell) |
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Strain of Origin:
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129S1/Sv-Oca2+ Tyr+ Kitl+
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Mutation
description |
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Allele
Type: | |
Targeted (Reporter) |
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Mutation: | |
Insertion |
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Mutation details: Exon 2 was disrupted by the insertion of a cassette containing EGFP and neo (in inverse orientation). Western blot analysis of splenocytes did not detect protein gene product. EGFP expression was not reported. (J:95334)
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Phenotypes
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View phenotypes for all genotypes (concatenated display).
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Disease models
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| Find Mice (IMSR) |
Mouse strains and cell lines available from the
International Mouse Strain Resource
(IMSR)
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Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available |
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Carrying any Dok2 Mutation:
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2 strains or lines available |
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| References |
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Original: |
J:95334
Niki M et al.,
"Role of Dok-1 and Dok-2 in leukemia suppression."
J Exp Med 2004 Dec 20;200(12):1689-95
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All: |
3 reference(s)
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Analysis Tools
